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Explore the latest news
from and about Sanford Labs.

Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial Publication

Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and...

  • August 18, 2025
  • Nature Communications
Evaluation of novel computational methods to identify RNA-binding protein footprints from structural data Publication

Evaluation of novel computational methods to identify RNA-binding protein footprints from structural data

  • May 21, 2025
  • RNA
Identification of RBP binding sites using RNA deaminases Publication

Identification of RBP binding sites using RNA deaminases

  • April 16, 2025
  • Methods in Enzymology
Short 5’ UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral complex Publication

Short 5’ UTRs serve as a marker for viral mRNA translation inhibition by the IFIT2-IFIT3 antiviral...

  • February 11, 2025
  • bioRxiv
Phenylpyrazoles as Inhibitors of the m6A RNA-Binding Protein YTHDF2 Publication

Phenylpyrazoles as Inhibitors of the m6A RNA-Binding Protein YTHDF2

  • February 10, 2025
  • JACS Au
Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes Publication

Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset...

  • October 31, 2024
  • Neuron
How AI can help deliver the next generation of RNA medicines Sanford Labs News

How AI can help deliver the next generation of RNA medicines

  • October 29, 2024
Integrated multi-omics analysis of zinc-finger proteins uncovers roles in RNA regulation Publication

Integrated multi-omics analysis of zinc-finger proteins uncovers roles in RNA regulation

  • October 3, 2024
  • Molecular Cell
Large-scale map of RNA-binding protein interactomes across the mRNA life cycle Publication

Large-scale map of RNA-binding protein interactomes across the mRNA life cycle

  • October 3, 2024
  • Molecular Cell
Decoding protein–RNA interactions using CLIP-based methodologies Publication

Decoding protein–RNA interactions using CLIP-based methodologies

  • July 9, 2024
  • Nature Reviews Genetics
Protocol to process crosslinking and immunoprecipitation data into annotated binding sites Publication

Protocol to process crosslinking and immunoprecipitation data into annotated binding sites

  • June 21, 2024
  • STAR Protocols
Long-read Ribo-STAMP simultaneously measures transcription and translation with isoform resolution Publication

Long-read Ribo-STAMP simultaneously measures transcription and translation with isoform resolution

  • June 21, 2024
  • Genome Research
Harnessing the momentum in RNA innovation Sanford Labs News

Harnessing the momentum in RNA innovation

  • June 1, 2024
Academia Europaea recognizes Gene Yeo with the Inaugural Sydney Brenner Medal In the News

Academia Europaea recognizes Gene Yeo with the Inaugural Sydney Brenner Medal

  • November 15, 2023
  • UC San Diego
Sanford Labs partners with UC San Diego Venture Fellows Sanford Labs News

Sanford Labs partners with UC San Diego Venture Fellows

  • October 30, 2023
Sanford Labs launches to propel breakthrough scientific discoveries to patients Sanford Labs News

Sanford Labs launches to propel breakthrough scientific discoveries to patients

  • July 1, 2023
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